Salisbury Middle is a public school located in Salisbury, MD. The student population of Salisbury Middle is just over 850 and the school serves grades 6 through 8. SMS also houses the school district's NeXgen Academy. The school’s student-teacher ratio is 14:1, and the student population is made up of 45% female students and 55% male students. There are 87 equivalent full-time teachers and 2 full-time school counselors.

The current Salisbury Middle School building is the former home of the Wicomico Applied Technology Center and the former all African-American Salisbury High School.